Prevalence, diversity, and host associations of Bartonella strains in bats from Georgia (Caucasus)

Lela Urushadze; Ying Bai; Lynn Osikowicz; Clifton McKee; Ketevan Sidamonidze; Davit Putkaradze; Paata Imnadze; Andrei Kandaurov; Ivan Kuzmin; Michael Kosoy

doi:10.1371/journal.pntd.0005428

Prevalence, diversity, and host associations of Bartonella strains in bats from Georgia (Caucasus)

Lela Urushadze, Ying Bai, Lynn Osikowicz, Clifton McKee, Ketevan Sidamonidze, Davit Putkaradze, Paata Imnadze, Andrei Kandaurov, Ivan Kuzmin, Michael Kosoy

Research output: Contribution to journal › Article › peer-review

Abstract

Bartonella infections were investigated in seven species of bats from four regions of the Republic of Georgia. Of the 236 bats that were captured, 212 (90%) specimens were tested for Bartonella infection. Colonies identified as Bartonella were isolated from 105 (49.5%) of 212 bats Phylogenetic analysis based on sequence variation of the gltA gene differentiated 22 unique Bartonella genogroups. Genetic distances between these diverse genogroups were at the level of those observed between different Bartonella species described previously. Twenty-one reference strains from 19 representative genogroups were characterized using four additional genetic markers. Host specificity to bat genera or families was reported for several Bartonella genogroups. Some Bartonella genotypes found in bats clustered with those identified in dogs from Thailand and humans from Poland.

Original language	English (US)
Article number	e0005428
Journal	PLoS neglected tropical diseases
Volume	11
Issue number	4
DOIs	https://doi.org/10.1371/journal.pntd.0005428
State	Published - Apr 11 2017
Externally published	Yes

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health
Infectious Diseases

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abstract = "Bartonella infections were investigated in seven species of bats from four regions of the Republic of Georgia. Of the 236 bats that were captured, 212 (90%) specimens were tested for Bartonella infection. Colonies identified as Bartonella were isolated from 105 (49.5%) of 212 bats Phylogenetic analysis based on sequence variation of the gltA gene differentiated 22 unique Bartonella genogroups. Genetic distances between these diverse genogroups were at the level of those observed between different Bartonella species described previously. Twenty-one reference strains from 19 representative genogroups were characterized using four additional genetic markers. Host specificity to bat genera or families was reported for several Bartonella genogroups. Some Bartonella genotypes found in bats clustered with those identified in dogs from Thailand and humans from Poland.",

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AU - Bai, Ying

AU - Osikowicz, Lynn

AU - McKee, Clifton

AU - Sidamonidze, Ketevan

AU - Putkaradze, Davit

AU - Imnadze, Paata

AU - Kandaurov, Andrei

AU - Kuzmin, Ivan

AU - Kosoy, Michael

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AB - Bartonella infections were investigated in seven species of bats from four regions of the Republic of Georgia. Of the 236 bats that were captured, 212 (90%) specimens were tested for Bartonella infection. Colonies identified as Bartonella were isolated from 105 (49.5%) of 212 bats Phylogenetic analysis based on sequence variation of the gltA gene differentiated 22 unique Bartonella genogroups. Genetic distances between these diverse genogroups were at the level of those observed between different Bartonella species described previously. Twenty-one reference strains from 19 representative genogroups were characterized using four additional genetic markers. Host specificity to bat genera or families was reported for several Bartonella genogroups. Some Bartonella genotypes found in bats clustered with those identified in dogs from Thailand and humans from Poland.

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Prevalence, diversity, and host associations of Bartonella strains in bats from Georgia (Caucasus)

Abstract

ASJC Scopus subject areas

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