Presence of γE in nasal washings and sputum from asthmatic patients

Kimishige Ishizaka; Richard W. Newcomb

doi:10.1016/0021-8707(70)90023-7

Presence of γE in nasal washings and sputum from asthmatic patients

Kimishige Ishizaka, Richard W. Newcomb

School of Medicine

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Abstract

Immunoglobulin E (γE) was detected in nasal washings and sputum obtained from some asthmatic patients. The measurement of γE concentration was not affected by the presence of enzymes or insoluble components of the exocrine fluids. Quantitatively, the γE γG concentration ratios in the specimens were usually higher than those in sera of the same patients. The results suggested the possibility that locally formed γE may be secreted, at least in part, into nasal fluids and sputum.

Original language	English (US)
Pages (from-to)	197-204
Number of pages	8
Journal	Journal of Allergy
Volume	46
Issue number	4
DOIs	https://doi.org/10.1016/0021-8707(70)90023-7
State	Published - Oct 1970

ASJC Scopus subject areas

Medicine(all)

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10.1016/0021-8707(70)90023-7

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title = "Presence of γE in nasal washings and sputum from asthmatic patients",

abstract = "Immunoglobulin E (γE) was detected in nasal washings and sputum obtained from some asthmatic patients. The measurement of γE concentration was not affected by the presence of enzymes or insoluble components of the exocrine fluids. Quantitatively, the γE γG concentration ratios in the specimens were usually higher than those in sera of the same patients. The results suggested the possibility that locally formed γE may be secreted, at least in part, into nasal fluids and sputum.",

author = "Kimishige Ishizaka and Newcomb, {Richard W.}",

note = "Funding Information: From the Children{\textquoteright}s Asthma Research Institute and Hospital. Supported by a research grant from the John A. Hartford Public Health Service @rant AI-08500. Received for publication Nov. 26, 1969. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",

year = "1970",

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doi = "10.1016/0021-8707(70)90023-7",

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AU - Ishizaka, Kimishige

AU - Newcomb, Richard W.

N1 - Funding Information: From the Children’s Asthma Research Institute and Hospital. Supported by a research grant from the John A. Hartford Public Health Service @rant AI-08500. Received for publication Nov. 26, 1969. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.

PY - 1970/10

Y1 - 1970/10

N2 - Immunoglobulin E (γE) was detected in nasal washings and sputum obtained from some asthmatic patients. The measurement of γE concentration was not affected by the presence of enzymes or insoluble components of the exocrine fluids. Quantitatively, the γE γG concentration ratios in the specimens were usually higher than those in sera of the same patients. The results suggested the possibility that locally formed γE may be secreted, at least in part, into nasal fluids and sputum.

AB - Immunoglobulin E (γE) was detected in nasal washings and sputum obtained from some asthmatic patients. The measurement of γE concentration was not affected by the presence of enzymes or insoluble components of the exocrine fluids. Quantitatively, the γE γG concentration ratios in the specimens were usually higher than those in sera of the same patients. The results suggested the possibility that locally formed γE may be secreted, at least in part, into nasal fluids and sputum.

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ER -

Presence of γE in nasal washings and sputum from asthmatic patients

Abstract

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