Preparation of subviral particles from vaccinia virions irradiated with ultraviolet light

M. Soloski, J. A. Holowczak

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Nucleoprotein complexes, containing proteins covalently bound to DNA, were prepared from vaccinia virions irradiated with ultraviolet light. In the electron microscope, these complexes were observed to have a spherical morphology with a densely staining central portion, apparently containing proteins cross-linked to DNA, from which loops or fibers of DNA or DNA complexed with protein emerged.

Original languageEnglish (US)
Pages (from-to)185-195
Number of pages11
JournalJournal of Virological Methods
Volume1
Issue number4
DOIs
StatePublished - 1980
Externally publishedYes

ASJC Scopus subject areas

  • Virology

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