Prenatal diagnosis of down syndrome: How best to deliver the news

Brian G. Skotko, Priya S. Kishnani, George T. Capone

Research output: Contribution to journalReview articlepeer-review

59 Scopus citations


We sought to provide evidence-based recommendations to physicians on how to best deliver a prenatal diagnosis of DS to expectant parents. Our study design consisted of searching Medline and PsychInfo from 1960 to 2008, as well as Web sites from academic organizations and other nonprofit or private organizations, using the terms "Down syndrome," "Trisomy 21," "mongolism," "prenatal diagnosis," "postnatal care," and "delivery of health care." Our results showed that a health care professional knowledgeable about DS with specific training in the delivery of sensitive diagnoses should be part of the first conversation. A prenatal diagnosis of DS should be presented in person or at a pre-established time by phone. Physicians should provide accurate information about medical conditions associated with DSand connect parents to local DS support groups and other resources. We conclude that physicians can deliver prenatal diagnoses of DS in a sensitive manner that can be appreciated by expectant parents.

Original languageEnglish (US)
Pages (from-to)2361-2367
Number of pages7
JournalAmerican Journal of Medical Genetics, Part A
Issue number11
StatePublished - Nov 2009


  • Delivery of health care
  • Down syndrome
  • Mongolism
  • Postnatal care
  • Prenatal diagnosis
  • Trisomy 21

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)


Dive into the research topics of 'Prenatal diagnosis of down syndrome: How best to deliver the news'. Together they form a unique fingerprint.

Cite this