Preliminary, Real-world, Multicenter Experience with Omadacycline for Mycobacterium abscessus Infections

Taylor Morrisette; Sara Alosaimy; Julie V. Philley; Carly Wadle; Catessa Howard; Andrew J. Webb; Michael P. Veve; Melissa L. Barger; Jeannette Bouchard; Tristan W. Gore; Abdalhamid M. Lagnf; Iman Ansari; Carlos Mejia-Chew; Keira A. Cohen; Michael J. Rybak

doi:10.1093/ofid/ofab002

Preliminary, Real-world, Multicenter Experience with Omadacycline for Mycobacterium abscessus Infections

Taylor Morrisette
, Sara Alosaimy
, Julie V. Philley
, Carly Wadle
, Catessa Howard
, Andrew J. Webb
, Michael P. Veve
, Melissa L. Barger
, Jeannette Bouchard
, Tristan W. Gore
, Abdalhamid M. Lagnf
, Iman Ansari
, Carlos Mejia-Chew
, Keira A. Cohen
, Michael J. Rybak

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Twelve patients were treated with omadacycline (OMC) as part of a multidrug regimen for Mycobacterium abscessus. The majority of infections were of pulmonary origin (7/12; 58.3%). The median (interquartile range) duration of OMC was 6.2 (4.2-11.0) months. Clinical success occurred in 9/12 (75.0%) patients. Three patients experienced a possible adverse effect while on therapy.

Original language	English (US)
Article number	ofab002
Journal	Open Forum Infectious Diseases
Volume	8
Issue number	2
DOIs	https://doi.org/10.1093/ofid/ofab002
State	Published - Feb 1 2021

Keywords

Mycobacterium abscessus
omadacycline
rapidly growing nontuberculous mycobacteria

ASJC Scopus subject areas

Oncology
Infectious Diseases

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10.1093/ofid/ofab002

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Morrisette, T., Alosaimy, S., Philley, J. V., Wadle, C., Howard, C., Webb, A. J., Veve, M. P., Barger, M. L., Bouchard, J., Gore, T. W., Lagnf, A. M., Ansari, I., Mejia-Chew, C., Cohen, K. A., & Rybak, M. J. (2021). Preliminary, Real-world, Multicenter Experience with Omadacycline for Mycobacterium abscessus Infections. Open Forum Infectious Diseases, 8(2), Article ofab002. https://doi.org/10.1093/ofid/ofab002

Morrisette, T, Alosaimy, S, Philley, JV, Wadle, C, Howard, C, Webb, AJ, Veve, MP, Barger, ML, Bouchard, J, Gore, TW, Lagnf, AM, Ansari, I, Mejia-Chew, C, Cohen, KA & Rybak, MJ 2021, 'Preliminary, Real-world, Multicenter Experience with Omadacycline for Mycobacterium abscessus Infections', Open Forum Infectious Diseases, vol. 8, no. 2, ofab002. https://doi.org/10.1093/ofid/ofab002

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AU - Webb, Andrew J.

AU - Veve, Michael P.

AU - Barger, Melissa L.

AU - Bouchard, Jeannette

AU - Gore, Tristan W.

AU - Lagnf, Abdalhamid M.

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AU - Mejia-Chew, Carlos

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KW - omadacycline

KW - rapidly growing nontuberculous mycobacteria

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Preliminary, Real-world, Multicenter Experience with Omadacycline for Mycobacterium abscessus Infections

Abstract

Keywords

ASJC Scopus subject areas

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