Preliminary findings: Neural responses to feedback regarding betrayal and cooperation in adolescent anxiety disorders

Erin B. McClure-Tone; Norberto E. Nawa; Eric E. Nelson; Allison M. Detloff; Stephen J. Fromm; Daniel S. Pine; Monique Ernst

doi:10.1080/87565641.2010.549876

Preliminary findings: Neural responses to feedback regarding betrayal and cooperation in adolescent anxiety disorders

Erin B. McClure-Tone, Norberto E. Nawa, Eric E. Nelson, Allison M. Detloff, Stephen J. Fromm, Daniel S. Pine, Monique Ernst

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

We compared neural and behavioral responses to feedback received during interpersonal interactions within the Prisoner's Dilemma game between adolescents with anxiety disorders (n = 12) and healthy peers (n = 17). Groups differed significantly in neural activation in the medial prefrontal cortex (mPFC), anterior cingulate cortex (ACC), precuneus, insula, and temporoparietal junction (TPJ). Anxious adolescents were also more likely than controls to cooperate after co-player betrayal. Our findings provide evidence that social behavior and related neural activity differs between anxious and healthy adolescents. These findings constitute a step toward elucidating neural correlates of social impairment in anxious youths.

Original language	English (US)
Pages (from-to)	453-472
Number of pages	20
Journal	Developmental Neuropsychology
Volume	36
Issue number	4
DOIs	https://doi.org/10.1080/87565641.2010.549876
State	Published - May 2011
Externally published	Yes

ASJC Scopus subject areas

Neuropsychology and Physiological Psychology
Developmental and Educational Psychology

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10.1080/87565641.2010.549876

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title = "Preliminary findings: Neural responses to feedback regarding betrayal and cooperation in adolescent anxiety disorders",

abstract = "We compared neural and behavioral responses to feedback received during interpersonal interactions within the Prisoner's Dilemma game between adolescents with anxiety disorders (n = 12) and healthy peers (n = 17). Groups differed significantly in neural activation in the medial prefrontal cortex (mPFC), anterior cingulate cortex (ACC), precuneus, insula, and temporoparietal junction (TPJ). Anxious adolescents were also more likely than controls to cooperate after co-player betrayal. Our findings provide evidence that social behavior and related neural activity differs between anxious and healthy adolescents. These findings constitute a step toward elucidating neural correlates of social impairment in anxious youths.",

author = "McClure-Tone, {Erin B.} and Nawa, {Norberto E.} and Nelson, {Eric E.} and Detloff, {Allison M.} and Fromm, {Stephen J.} and Pine, {Daniel S.} and Monique Ernst",

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AU - Nawa, Norberto E.

AU - Nelson, Eric E.

AU - Detloff, Allison M.

AU - Fromm, Stephen J.

AU - Pine, Daniel S.

AU - Ernst, Monique

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Preliminary findings: Neural responses to feedback regarding betrayal and cooperation in adolescent anxiety disorders

Abstract

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