Predictors of pain and fatigue in the year following diagnosis among elderly cancer patients

Charles W. Given, Barbara Given, Faouzi Azzouz, Sharon Kozachik, Manfred Stommel

Research output: Contribution to journalArticlepeer-review

161 Scopus citations


Using data obtained from an inception cohort of 841 patients aged 65 or older newly diagnosed with breast, colon, lung, or prostate cancer, and observed at 6-8, 12-16, 24-30, and 52 weeks, three questions related to patients' experiences with pain and fatigue were posed. First, how do numbers of patients reporting neither pain nor fatigue, either symptom, or both change during the observation year? Second, did number of comorbid conditions, site and stage of cancer, treatment modalities, symptom management medication, and time affect the presence of these two symptoms? Third, do pain and fatigue predict the numbers of co-occurring other symptoms? Findings indicate that during the year patients improved with respect to their reports of pain and/or fatigue. Stage, more comorbidity, and lung cancer were related to both pain and fatigue. Chemotherapy was related to reports of fatigue, but did not have an extended effect on fatigue.

Original languageEnglish (US)
Pages (from-to)456-466
Number of pages11
JournalJournal of Pain and Symptom Management
Issue number6
StatePublished - 2001
Externally publishedYes


  • Fatigue
  • Inception cohort
  • Longitudinal analysis
  • Pain

ASJC Scopus subject areas

  • Nursing(all)
  • Clinical Neurology
  • Anesthesiology and Pain Medicine


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