Prediction of Graft versus Host Disease

Michael S. Kennedy, Georgia B. Vogelsang, Allan D. Hess, George W. Santos

Research output: Contribution to journalLetterpeer-review


To the Editor: The article by Vogelsang et al. (September 12 issue)1 contains interesting data regarding an in vitro test to predict clinical graft versus host disease (GVHD). It would appear, however, that this test may not be useful in patients receiving cyclosporine as prophylaxis against the disease. It is unfortunate that this test was applied in a tremendously heterogeneous group of patients. The ages, diagnoses, conditioning regimens, and most important, the prophylactic regimens were not uniform. The Johns Hopkins group has previously reported that the risk of GVHD was increased in patients with acute lymphocytic leukemia or sex-mismatched grafts.

Original languageEnglish (US)
Pages (from-to)718-719
Number of pages2
JournalNew England Journal of Medicine
Issue number11
StatePublished - Mar 13 1986

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Prediction of Graft versus Host Disease'. Together they form a unique fingerprint.

Cite this