Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions

Ibolja Cernak; Donald G. Stein; Gregory A. Elder; Stephn Ahlers; Kenneth Curley; Ralph G. DePalma; John Duda; Milos Ikonomovic; Grant L. Iverson; Firas Kobeissy; Vassilis E. Koliatsos; Michael J. Leggieri; Anthony M. Pacifico; Douglas H. Smith; Raymond Swanson; Floyd J. Thompson; Frank C. Tortella

doi:10.1080/02699052.2016.1274779

Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions

Ibolja Cernak, Donald G. Stein, Gregory A. Elder, Stephn Ahlers, Kenneth Curley, Ralph G. DePalma, John Duda, Milos Ikonomovic, Grant L. Iverson, Firas Kobeissy, Vassilis E. Koliatsos, Michael J. Leggieri, Anthony M. Pacifico, Douglas H. Smith, Raymond Swanson, Floyd J. Thompson, Frank C. Tortella

School of Medicine

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

As a follow-up to the 2008 state-of-the-art (SOTA) conference on traumatic brain injuries (TBIs), the 2015 event organized by the United States Department of Veterans Affairs (VA) Office of Research and Development (ORD) analysed the knowledge gained over the last 7 years as it relates to basic scientific methods, experimental findings, diagnosis, therapy, and rehabilitation of TBIs and blast-induced neurotraumas (BINTs). The current article summarizes the discussions and recommendations of the scientific panel attending the Preclinical Modeling and Therapeutic Development Workshop of the conference, with special emphasis on factors slowing research progress and recommendations for ways of addressing the most significant pitfalls.

Original language	English (US)
Pages (from-to)	1168-1176
Number of pages	9
Journal	Brain Injury
Volume	31
Issue number	9
DOIs	https://doi.org/10.1080/02699052.2016.1274779
State	Published - Jul 29 2017

Keywords

United States Department of Veterans Affairs
blast-induced neurotrauma
conference
experimental models
preclinical research
traumatic brain injury

ASJC Scopus subject areas

Neuroscience (miscellaneous)
Developmental and Educational Psychology
Clinical Neurology

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10.1080/02699052.2016.1274779

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Cernak, I., Stein, D. G., Elder, G. A., Ahlers, S., Curley, K., DePalma, R. G., Duda, J., Ikonomovic, M., Iverson, G. L., Kobeissy, F., Koliatsos, V. E., Leggieri, M. J., Pacifico, A. M., Smith, D. H., Swanson, R., Thompson, F. J., & Tortella, F. C. (2017). Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions. Brain Injury, 31(9), 1168-1176. https://doi.org/10.1080/02699052.2016.1274779

Cernak, I, Stein, DG, Elder, GA, Ahlers, S, Curley, K, DePalma, RG, Duda, J, Ikonomovic, M, Iverson, GL, Kobeissy, F, Koliatsos, VE, Leggieri, MJ, Pacifico, AM, Smith, DH, Swanson, R, Thompson, FJ & Tortella, FC 2017, 'Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions', Brain Injury, vol. 31, no. 9, pp. 1168-1176. https://doi.org/10.1080/02699052.2016.1274779

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AU - DePalma, Ralph G.

AU - Duda, John

AU - Ikonomovic, Milos

AU - Iverson, Grant L.

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AU - Koliatsos, Vassilis E.

AU - Leggieri, Michael J.

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Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions

Abstract

Keywords

ASJC Scopus subject areas

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