Pre-Operative Localization of Axillary Lymph Nodes with Tattoo Ink: A Preliminary Report

Kelly Myers; Sachin Aggarwal; Eniola T. Oluyemi; Mehran Habibi; Emily B. Ambinder; Armina Azizi; Parvinder Sujlana; Jessica Hung; Nagi Fouad Khouri; David Jon Eisner; Philip A. Di Carlo; Ashley M. Cimino-Mathews; Melissa S. Camp

doi:10.32768/abc.202182143-148

Pre-Operative Localization of Axillary Lymph Nodes with Tattoo Ink: A Preliminary Report

Kelly Myers, Sachin Aggarwal, Eniola T. Oluyemi, Mehran Habibi, Emily B. Ambinder, Armina Azizi, Parvinder Sujlana, Jessica Hung, Nagi Fouad Khouri, David Jon Eisner, Philip A. Di Carlo, Ashley M. Cimino-Mathews, Melissa S. Camp

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Pre-operative localization options in the axilla are limited. This study aimed to explore the utility of pre-operative localization of axillary lymph nodes using tattoo ink with multidisciplinary correlations. Methods: In this prospective, Institutional Review Board (IRB)-approved study, 19 lymph nodes in 17 patients underwent pre-operative localization with ultrasound-guided injection of Spot tattoo ink. The success rate of intraoperative identification of the tattooed node as well as the frequency in which the tattooed node was also a sentinel node were recorded. Radiologic, surgical and pathologic images were collected. Results: Tattoo ink localization was successful in 16/17 (94.1%) of patients. Tattoo ink did not hinder pathologic evaluation in any cases but was taken up by additional adjacent nodes in 1/17 successful localizations (5.9%). Successful sentinel lymph node biopsy (SLNB) occurred in 13 patients in whom 14 lymph nodes underwent pre-operative tattoo ink localization. Nine of the 14 (64.2%) tattooed lymph nodes were also a sentinel node. Conclusion: In this study, pre-operative localization of axillary lymph nodes with tattoo ink was highly successful In patients undergoing SLNB, a significant number of the tattooed nodes were not sentinel nodes (35.8%), suggesting the importance of targeted lymph node excision in addition to SLNB.

Original language	English (US)
Pages (from-to)	143-148
Number of pages	6
Journal	Archives of Breast Cancer
Volume	8
Issue number	2
DOIs	https://doi.org/10.32768/abc.202182143-148
State	Published - May 1 2021

Keywords

Axilla
ink
interventional ultrasonography
pre-operative localization
sentinel Lymph node

ASJC Scopus subject areas

Oncology
Cancer Research
Pathophysiology
Genetics
Molecular Biology
Epidemiology

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10.32768/abc.202182143-148

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Myers, K., Aggarwal, S., Oluyemi, E. T., Habibi, M., Ambinder, E. B., Azizi, A., Sujlana, P., Hung, J., Khouri, N. F., Eisner, D. J., Di Carlo, P. A., Cimino-Mathews, A. M., & Camp, M. S. (2021). Pre-Operative Localization of Axillary Lymph Nodes with Tattoo Ink: A Preliminary Report. Archives of Breast Cancer, 8(2), 143-148. https://doi.org/10.32768/abc.202182143-148

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title = "Pre-Operative Localization of Axillary Lymph Nodes with Tattoo Ink: A Preliminary Report",

abstract = "Background: Pre-operative localization options in the axilla are limited. This study aimed to explore the utility of pre-operative localization of axillary lymph nodes using tattoo ink with multidisciplinary correlations. Methods: In this prospective, Institutional Review Board (IRB)-approved study, 19 lymph nodes in 17 patients underwent pre-operative localization with ultrasound-guided injection of Spot tattoo ink. The success rate of intraoperative identification of the tattooed node as well as the frequency in which the tattooed node was also a sentinel node were recorded. Radiologic, surgical and pathologic images were collected. Results: Tattoo ink localization was successful in 16/17 (94.1%) of patients. Tattoo ink did not hinder pathologic evaluation in any cases but was taken up by additional adjacent nodes in 1/17 successful localizations (5.9%). Successful sentinel lymph node biopsy (SLNB) occurred in 13 patients in whom 14 lymph nodes underwent pre-operative tattoo ink localization. Nine of the 14 (64.2%) tattooed lymph nodes were also a sentinel node. Conclusion: In this study, pre-operative localization of axillary lymph nodes with tattoo ink was highly successful In patients undergoing SLNB, a significant number of the tattooed nodes were not sentinel nodes (35.8%), suggesting the importance of targeted lymph node excision in addition to SLNB.",

keywords = "Axilla, ink, interventional ultrasonography, pre-operative localization, sentinel Lymph node",

author = "Kelly Myers and Sachin Aggarwal and Oluyemi, {Eniola T.} and Mehran Habibi and Ambinder, {Emily B.} and Armina Azizi and Parvinder Sujlana and Jessica Hung and Khouri, {Nagi Fouad} and Eisner, {David Jon} and {Di Carlo}, {Philip A.} and Cimino-Mathews, {Ashley M.} and Camp, {Melissa S.}",

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year = "2021",

month = may,

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doi = "10.32768/abc.202182143-148",

language = "English (US)",

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T1 - Pre-Operative Localization of Axillary Lymph Nodes with Tattoo Ink

T2 - A Preliminary Report

AU - Myers, Kelly

AU - Aggarwal, Sachin

AU - Oluyemi, Eniola T.

AU - Habibi, Mehran

AU - Ambinder, Emily B.

AU - Azizi, Armina

AU - Sujlana, Parvinder

AU - Hung, Jessica

AU - Khouri, Nagi Fouad

AU - Eisner, David Jon

AU - Di Carlo, Philip A.

AU - Cimino-Mathews, Ashley M.

AU - Camp, Melissa S.

PY - 2021/5/1

Y1 - 2021/5/1

N2 - Background: Pre-operative localization options in the axilla are limited. This study aimed to explore the utility of pre-operative localization of axillary lymph nodes using tattoo ink with multidisciplinary correlations. Methods: In this prospective, Institutional Review Board (IRB)-approved study, 19 lymph nodes in 17 patients underwent pre-operative localization with ultrasound-guided injection of Spot tattoo ink. The success rate of intraoperative identification of the tattooed node as well as the frequency in which the tattooed node was also a sentinel node were recorded. Radiologic, surgical and pathologic images were collected. Results: Tattoo ink localization was successful in 16/17 (94.1%) of patients. Tattoo ink did not hinder pathologic evaluation in any cases but was taken up by additional adjacent nodes in 1/17 successful localizations (5.9%). Successful sentinel lymph node biopsy (SLNB) occurred in 13 patients in whom 14 lymph nodes underwent pre-operative tattoo ink localization. Nine of the 14 (64.2%) tattooed lymph nodes were also a sentinel node. Conclusion: In this study, pre-operative localization of axillary lymph nodes with tattoo ink was highly successful In patients undergoing SLNB, a significant number of the tattooed nodes were not sentinel nodes (35.8%), suggesting the importance of targeted lymph node excision in addition to SLNB.

AB - Background: Pre-operative localization options in the axilla are limited. This study aimed to explore the utility of pre-operative localization of axillary lymph nodes using tattoo ink with multidisciplinary correlations. Methods: In this prospective, Institutional Review Board (IRB)-approved study, 19 lymph nodes in 17 patients underwent pre-operative localization with ultrasound-guided injection of Spot tattoo ink. The success rate of intraoperative identification of the tattooed node as well as the frequency in which the tattooed node was also a sentinel node were recorded. Radiologic, surgical and pathologic images were collected. Results: Tattoo ink localization was successful in 16/17 (94.1%) of patients. Tattoo ink did not hinder pathologic evaluation in any cases but was taken up by additional adjacent nodes in 1/17 successful localizations (5.9%). Successful sentinel lymph node biopsy (SLNB) occurred in 13 patients in whom 14 lymph nodes underwent pre-operative tattoo ink localization. Nine of the 14 (64.2%) tattooed lymph nodes were also a sentinel node. Conclusion: In this study, pre-operative localization of axillary lymph nodes with tattoo ink was highly successful In patients undergoing SLNB, a significant number of the tattooed nodes were not sentinel nodes (35.8%), suggesting the importance of targeted lymph node excision in addition to SLNB.

KW - Axilla

KW - ink

KW - interventional ultrasonography

KW - pre-operative localization

KW - sentinel Lymph node

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JF - Archives of Breast Cancer

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Pre-Operative Localization of Axillary Lymph Nodes with Tattoo Ink: A Preliminary Report

Abstract

Keywords

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