@article{9d58a5d48a704652880d75bd56074f0d,
title = "Postpartum depression biomarkers predict exacerbation of OCD symptoms during pregnancy",
keywords = "HP1BP3, Obsessive compulsive disorder, TTC9B, biomarkers, epigenetics, postpartum depression, pregnancy",
author = "Kaminsky, \{Zachary A.\} and Osborne, \{Lauren M.\} and Valeria Guglielmi and Ilenna Jones and Winston Grenier and Karen Clark and Evelyn Ross and Samantha Meilman and Paul Nestadt and Payne, \{Jennifer L.\} and Jack Samuels and Gerald Nestadt",
note = "Funding Information: Z.K. and J.P. are listed as investors on a patent to use the above biomarkers to predict postpartum depression. Z.K. is the founder of and holds equity in METHYX LLC. He also serves as the company's Managing Member. METHYX LLC intends to license technology used in the study that is described in this publication. This arrangement has been reviewed and approved by the Johns Hopkins University in accordance with its conflict of interest policies. J.P. received legal consulting fees from Astra Zeneca, Eli Lilly, Johnson \& Johnson, and Abbott Pharmaceuticals and received research support from the NIMH, the Stanley Medical Research Foundation, and SAGE Therapeutics. All other authors declare that they have no competing interests.We would like to thank The Solomon R. \& Rebecca D. Baker Foundation, DIFD, and the Mach-Gaensslen Foundation for their generous support of this research. This work was supported by a 2010 NARSAD Young Investigator Award, R01MH104262, K23 MH074799-01A2, R01-MH50214, R01-MH071507, NIH/NCRR/OPD-GCRC RR00052, and the James E. Marshall OCD Foundation. The Johns Hopkins University IRB approved this research and all subjects gave consent for the study. Prospective human subjects{\textquoteright} research for the Johns Hopkins Prospective PPD Cohort was conducted under IRB protocol \# 00008149. Prospective human subjects{\textquoteright} research for the Johns Hopkins BRAINS Neuroimaging Cohort was conducted under Johns Hopkins IRB protocols \# 00038271 and 00027369. Human subjects{\textquoteright} research for the OCD cohort was conducted under Johns Hopkins IRB protocol \# NA\_00039786/CR00013867. All protocols conform to the Declaration of Helsinki. Funding Information: We would like to thank The Solomon R. \& Rebecca D. Baker Foundation, DIFD, and the Mach-Gaensslen Foundation for their generous support of this research. This work was supported by a 2010 NARSAD Young Investigator Award, R01MH104262 , K23 MH074799-01A2 , R01-MH50214 , R01-MH071507 , NIH / NCRR /OPD-GCRC RR00052, and the James E. Marshall OCD Foundation . The Johns Hopkins University IRB approved this research and all subjects gave consent for the study. Prospective human subjects{\textquoteright} research for the Johns Hopkins Prospective PPD Cohort was conducted under IRB protocol \# 00008149. Prospective human subjects{\textquoteright} research for the Johns Hopkins BRAINS Neuroimaging Cohort was conducted under Johns Hopkins IRB protocols \# 00038271 and 00027369. Human subjects{\textquoteright} research for the OCD cohort was conducted under Johns Hopkins IRB protocol \# NA\_00039786/CR00013867. All protocols conform to the Declaration of Helsinki. ",
year = "2020",
month = nov,
doi = "10.1016/j.psychres.2020.113332",
language = "English (US)",
volume = "293",
journal = "Psychiatry research",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd",
}