TY - JOUR
T1 - Postoperative Stereotactic Body Radiation Therapy (SBRT) for Spine Metastases
T2 - A Critical Review to Guide Practice
AU - Redmond, Kristin J.
AU - Lo, Simon S.
AU - Fisher, Charles
AU - Sahgal, Arjun
N1 - Funding Information:
Conflict of interest: Drs Redmond, Sahgal, and Lo are members of an oligometastasis research consortium funded through a grant from Elekta AB. Dr Lo has received travel expenses and honoraria for past educational seminars from Varian Medical Systems and Accuray. Dr Fisher does consulting for Medtronic and Nuvasive, has received grants from Orthopedic research and education fund (OREF), and receives royalties from Medtronic. Dr Sahgal has research grants from Elekta AB and received honoraria for past educational seminars from Elekta AB, Medtronic, and Varian Medical Systems.
Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Postoperative stereotactic body radiation therapy (SBRT) for metastatic spinal tumors is increasingly being performed in clinical practice. Whereas the fundamentals of SBRT practice for intact spinal metastases are established, there are as yet no comprehensive practice guidelines for the postoperative indications. In particular, there are unique considerations for patient selection and treatment planning specific to postoperative spine SBRT that are critical for safe and effective management. The purpose of this critical review is to discuss the rationale for treatment, describe those factors affecting surgical decision making, introduce modern surgical trends, and summarize treatment outcomes for both conventional postoperative external beam radiation therapy and postoperative spine SBRT. Lastly, an in-depth practical discussion with respect to treatment planning and delivery considerations is provided to help guide optimal practice.
AB - Postoperative stereotactic body radiation therapy (SBRT) for metastatic spinal tumors is increasingly being performed in clinical practice. Whereas the fundamentals of SBRT practice for intact spinal metastases are established, there are as yet no comprehensive practice guidelines for the postoperative indications. In particular, there are unique considerations for patient selection and treatment planning specific to postoperative spine SBRT that are critical for safe and effective management. The purpose of this critical review is to discuss the rationale for treatment, describe those factors affecting surgical decision making, introduce modern surgical trends, and summarize treatment outcomes for both conventional postoperative external beam radiation therapy and postoperative spine SBRT. Lastly, an in-depth practical discussion with respect to treatment planning and delivery considerations is provided to help guide optimal practice.
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U2 - 10.1016/j.ijrobp.2016.03.027
DO - 10.1016/j.ijrobp.2016.03.027
M3 - Review article
C2 - 27479724
AN - SCOPUS:84990853772
SN - 0360-3016
VL - 95
SP - 1414
EP - 1428
JO - International Journal of Radiation Oncology Biology Physics
JF - International Journal of Radiation Oncology Biology Physics
IS - 5
ER -