Point-to-volume registration of prostate implants to ultrasound.

Ehsan Dehghan, Junghoon Lee, Pascal Fallavollita, Nathanael Kuo, Anton Deguet, E. Clif Burdette, Danny Song, Jerry L. Prince, Gabor Fichtinger

Research output: Chapter in Book/Report/Conference proceedingChapter


Ultrasound-Fluoroscopy fusion is a key step toward intraoperative dosimetry for prostate brachytherapy. We propose a method for intensity-based registration of fluoroscopy to ultrasound that obviates the need for seed segmentation required for seed-based registration. We employ image thresholding and morphological and Gaussian filtering to enhance the image intensity distribution of ultrasound volume. Finally, we find the registration parameters by maximizing a point-to-volume similarity metric. We conducted an experiment on a ground truth phantom and achieved registration error of 0.7 +/- 0.2 mm. Our clinical results on 5 patient data sets show excellent visual agreement between the registered seeds and the ultrasound volume with a seed-to-seed registration error of 1.8 +/- 0.9mm. With low registration error, high computational speed and no need for manual seed segmentation, our method is promising for clinical application.

Original languageEnglish (US)
Title of host publicationMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Number of pages8
EditionPt 2
StatePublished - 2011
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Point-to-volume registration of prostate implants to ultrasound.'. Together they form a unique fingerprint.

Cite this