Pluripotent stem cell-based cancer therapy: Promise and challenges

Saul J. Sharkis; Richard J. Jones; Curt Civin; Yoon Young Jang

doi:10.1126/scitranslmed.3003920

Pluripotent stem cell-based cancer therapy: Promise and challenges

Saul J. Sharkis, Richard J. Jones, Curt Civin, Yoon Young Jang

School of Medicine

Research output: Contribution to journal › Review article › peer-review

28 Scopus citations

Abstract

The development of induced pluripotent stem cell (iPSC) technology has generated enthusiasm about the therapeutic potential of these cells for treating a variety of diseases. However, the evidence that they actually will be clinically useful is limited. Here, we discuss the potential therapeutic applications of iPSCs for treating cancer and other diseases and highlight the current barriers restricting their use.

Original language	English (US)
Article number	127ps9
Journal	Science translational medicine
Volume	4
Issue number	127
DOIs	https://doi.org/10.1126/scitranslmed.3003920
State	Published - Mar 28 2012

ASJC Scopus subject areas

General Medicine

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10.1126/scitranslmed.3003920

Cite this

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title = "Pluripotent stem cell-based cancer therapy: Promise and challenges",

abstract = "The development of induced pluripotent stem cell (iPSC) technology has generated enthusiasm about the therapeutic potential of these cells for treating a variety of diseases. However, the evidence that they actually will be clinically useful is limited. Here, we discuss the potential therapeutic applications of iPSCs for treating cancer and other diseases and highlight the current barriers restricting their use.",

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AU - Civin, Curt

AU - Jang, Yoon Young

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AB - The development of induced pluripotent stem cell (iPSC) technology has generated enthusiasm about the therapeutic potential of these cells for treating a variety of diseases. However, the evidence that they actually will be clinically useful is limited. Here, we discuss the potential therapeutic applications of iPSCs for treating cancer and other diseases and highlight the current barriers restricting their use.

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Pluripotent stem cell-based cancer therapy: Promise and challenges

Abstract

ASJC Scopus subject areas

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