Pleomorphic xanthoastrocytoma in the posterior fossa: a case report with advanced neuroimaging findings

Licia Pacheco Luna; Isabelle Meneses da Ponte; Isabella Bezerra Oliveira; Francisco Ramos; Gunter Gerson

doi:10.1016/j.clinimag.2020.02.010

Pleomorphic xanthoastrocytoma in the posterior fossa: a case report with advanced neuroimaging findings

Licia Pacheco Luna, Isabelle Meneses da Ponte, Isabella Bezerra Oliveira, Francisco Ramos, Gunter Gerson

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Pleomorphic xanthoastrocytoma (PXA) is a rare glioma usually occurring in children and young adults. It is a benign World Health Organization (WHO) grade II tumor that accounts for <1% of all astrocytomas. Its occurrence in the infratentorial compartment is rare, and the cerebellum is the most common of the unusual locations. Few case reports have described conventional imaging features of these tumors, but none has reported the advanced magnetic resonance (MR) neuroimaging features in dynamic susceptibility perfusion-weighted imaging (DSC-PWI), diffusion weighted-imaging (DWI) and MR spectroscopy. Therefore, the purpose of this study is to report a case of PXA in the cerebellum of a 28-year-old patient and discuss the MR advanced imaging characteristics compared to the more common PXA supratentorial type.

Original language	English (US)
Pages (from-to)	30-34
Number of pages	5
Journal	Clinical Imaging
Volume	63
DOIs	https://doi.org/10.1016/j.clinimag.2020.02.010
State	Published - Jul 2020

Keywords

Advanced imaging
Infratentorial
MRI
Pleomorphic xanthoastrocytoma
Posterior fossa

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.clinimag.2020.02.010

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title = "Pleomorphic xanthoastrocytoma in the posterior fossa: a case report with advanced neuroimaging findings",

abstract = "Pleomorphic xanthoastrocytoma (PXA) is a rare glioma usually occurring in children and young adults. It is a benign World Health Organization (WHO) grade II tumor that accounts for <1% of all astrocytomas. Its occurrence in the infratentorial compartment is rare, and the cerebellum is the most common of the unusual locations. Few case reports have described conventional imaging features of these tumors, but none has reported the advanced magnetic resonance (MR) neuroimaging features in dynamic susceptibility perfusion-weighted imaging (DSC-PWI), diffusion weighted-imaging (DWI) and MR spectroscopy. Therefore, the purpose of this study is to report a case of PXA in the cerebellum of a 28-year-old patient and discuss the MR advanced imaging characteristics compared to the more common PXA supratentorial type.",

keywords = "Advanced imaging, Infratentorial, MRI, Pleomorphic xanthoastrocytoma, Posterior fossa",

author = "Luna, {Licia Pacheco} and {da Ponte}, {Isabelle Meneses} and Oliveira, {Isabella Bezerra} and Francisco Ramos and Gunter Gerson",

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year = "2020",

month = jul,

doi = "10.1016/j.clinimag.2020.02.010",

language = "English (US)",

volume = "63",

pages = "30--34",

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T2 - a case report with advanced neuroimaging findings

AU - Luna, Licia Pacheco

AU - da Ponte, Isabelle Meneses

AU - Oliveira, Isabella Bezerra

AU - Ramos, Francisco

AU - Gerson, Gunter

PY - 2020/7

Y1 - 2020/7

N2 - Pleomorphic xanthoastrocytoma (PXA) is a rare glioma usually occurring in children and young adults. It is a benign World Health Organization (WHO) grade II tumor that accounts for <1% of all astrocytomas. Its occurrence in the infratentorial compartment is rare, and the cerebellum is the most common of the unusual locations. Few case reports have described conventional imaging features of these tumors, but none has reported the advanced magnetic resonance (MR) neuroimaging features in dynamic susceptibility perfusion-weighted imaging (DSC-PWI), diffusion weighted-imaging (DWI) and MR spectroscopy. Therefore, the purpose of this study is to report a case of PXA in the cerebellum of a 28-year-old patient and discuss the MR advanced imaging characteristics compared to the more common PXA supratentorial type.

AB - Pleomorphic xanthoastrocytoma (PXA) is a rare glioma usually occurring in children and young adults. It is a benign World Health Organization (WHO) grade II tumor that accounts for <1% of all astrocytomas. Its occurrence in the infratentorial compartment is rare, and the cerebellum is the most common of the unusual locations. Few case reports have described conventional imaging features of these tumors, but none has reported the advanced magnetic resonance (MR) neuroimaging features in dynamic susceptibility perfusion-weighted imaging (DSC-PWI), diffusion weighted-imaging (DWI) and MR spectroscopy. Therefore, the purpose of this study is to report a case of PXA in the cerebellum of a 28-year-old patient and discuss the MR advanced imaging characteristics compared to the more common PXA supratentorial type.

KW - Advanced imaging

KW - Infratentorial

KW - MRI

KW - Pleomorphic xanthoastrocytoma

KW - Posterior fossa

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Pleomorphic xanthoastrocytoma in the posterior fossa: a case report with advanced neuroimaging findings

Abstract

Keywords

ASJC Scopus subject areas

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