Platypnea-orthodeoxia and progressive autonomic failure

J. L. Fox, E. Brown, J. K. Harrison, J. Williams, P. B. Terry

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Platypnea-orthodeoxia has been described in patients with pulmonary shunts, intracardiac shunts, and severe lung disease. We report a case of platypnea-orthodeoxia in a patient with minimal obstructive lung disease and progressive autonomic failure. We have shown our patient's syptoms to be the result of an orthostatic increase in ventilation-perfusion mismatching and to be corrected with fluid challenge.

Original languageEnglish (US)
Pages (from-to)1802-1804
Number of pages3
JournalAmerican Review of Respiratory Disease
Issue number6
StatePublished - 1989

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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