Plasminogen in peritoneal fluid: A possible nonsteroidal indicator of ovulation

S. L. Padilla, P. C. Galle, J. O. Ellegood, V. B. Mahesh, P. G. McDonough

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Plasminogen levels in peritoneal fluid were evaluated in 40 fertile women with regular ovulatory cycles. Fifteen samples were obtained before ovulation and 25 samples after ovulation. Plasminogen content and concentration in postovulatory peritoneal fluid was 0.84 ± 0.10 mg and 6.1 ± 0.57 mg/dl, respectively. These values were significantly higher than in the preovulatory peritoneal fluid, which were 0.36 ± 0.12 mg (P < 0.005) and 3.5 ± 0.33 mg/dl, (P < 0.001), respectively. Estradiol and progesterone (P) concentrations in peritoneal fluid were significantly higher after ovulation (P < 0.05 and P < 0.01, respectively). P concentration in serum and peritoneal fluid showed a linear correlation (P < 0.05). Peritoneal fluid plasminogen is significantly elevated after ovulation and may be a nonsteroidal marker for follicular rupture and oocyte extrusion.

Original languageEnglish (US)
Pages (from-to)1071-1076
Number of pages6
JournalFertility and sterility
Issue number6
StatePublished - 1986
Externally publishedYes

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology


Dive into the research topics of 'Plasminogen in peritoneal fluid: A possible nonsteroidal indicator of ovulation'. Together they form a unique fingerprint.

Cite this