Abstract
In a man with Fabry disease, basal plasma glycosphingolipid (GSL) levels were determined by high-performance liquid chromatography (HPLC). A series of three alternate-day plasma exchanges transiently lowered plasma ceramide trihexoside (CTH) to normal. A total of 70 μmoles of CTH were removed by eight plasma exchanges. If future studies show that pathologic tissue accumulations of CTK are reduced by plasma exchange, then long-term repetitive plasma exchange could be used as treatment until enzyme replacement is practical.
Original language | English (US) |
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Pages (from-to) | 301-307 |
Number of pages | 7 |
Journal | Unknown Journal |
Volume | 7 |
Issue number | 3 |
DOIs | |
State | Published - 1980 |
ASJC Scopus subject areas
- Genetics(clinical)