Abstract
Background and Aims: Many neurophysiologic effects have been observed during acupuncture. So far there is no placebo-controlled trial studying the correlation between changes in the central nervous system and vegetative effects. In consideration of a reliable blinding of the volunteers, the aim of this study was to examine specific cerebral and vegetative effects of verum-acupunture (VA) compared to placebo-acupuncture (PA). Methods: Healthy volunteers received either VA at LI 4 (Hegu) with a verum-needle or PA at a non-acupuncture point with a placebo needle. EEG and ECG recordings were performed in parallel followed by an evaluation of pain, skin penetration and vegetative effects. Results: The feeling of skin penetration was not significantly different (p = 0.057). Vegetative effects and Deqi occurred significantly more often during VA (p = 0.022). Pain was increased during VA-stimulation compared to PA (p > 0.01). Verum stimulation markedly increased occipital EEG power (p < 0.03). The increase in the fast alpha1 waves was accompanied by a decrease in the theta frequencies and the ratio alpha1/theta was shifted to the benefit of alpha1 (p < 0.04). This was paralleled by a short increase of the ECG ratio between low frequency (LF) and high frequency (HF) (p < 0.02), followed by an increase of HF-power (p < 0.04). Conclusions: Volunteers were unable to distinguish between VA and PA. The EEG and ECG changes measured during VA stimulation are pointing towards a modulation of cerebral functions by vegetative acupuncture effects compared to PA.
Translated title of the contribution | Placebo-controlled investigation of cerebral and vegetative effects of acupuncture at LI 4 |
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Original language | German |
Pages (from-to) | 12-19 |
Number of pages | 8 |
Journal | Deutsche Zeitschrift fur Akupunktur |
Volume | 51 |
Issue number | 4 |
DOIs | |
State | Published - Jan 1 2008 |
Externally published | Yes |
Keywords
- Acupuncture
- ECG
- EEG
- LI 4
- Placebo
ASJC Scopus subject areas
- Complementary and alternative medicine
- Clinical Neurology