Pica with paradichlorobenzene mothball ingestion associated with toxic leukoencephalopathy

Edward Avila, Paul Schraeder, Ajit Belliappa, Scott Faro

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


This is a case report of central nervous system toxicity associated with paradichlorobenzene (PDCB) ingestion. The patient had ingested mothballs composed of 99.99% PDCB for a period of 7 months. She was admitted for depression and had no neurologic symptoms. Later she developed an acute cerebellar syndrome followed by stupor and coma. An extensive workup was negative except for decreasing levels of PDCB in her serum. Imaging revealed a diffuse leukoencephalopathy. Her clinical picture was attributed to PDCB toxicity.

Original languageEnglish (US)
Pages (from-to)78-81
Number of pages4
JournalJournal of Neuroimaging
Issue number1
StatePublished - Jan 2006
Externally publishedYes


  • Central nervous system (CNS)
  • Leukoencephalopathy
  • Magnetic resonance spectroscopy
  • Mothballs
  • Paradichlorobenzene (PDCB)

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology


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