TY - JOUR
T1 - Physical Activity and Adiposity in a Racially Diverse Cohort of US Infants
AU - Benjamin-Neelon, Sara E.
AU - Bai, Jiawei
AU - Østbye, Truls
AU - Neelon, Brian
AU - Pate, Russell R.
AU - Crainiceanu, Ciprian
N1 - Funding Information:
This study was supported by a grant from the National Institutes of Health (R01DK094841). The funders had no role in the design of the study, data collection and analysis, decision to publish, or preparation of the manuscript.
Publisher Copyright:
© 2020 The Authors. Obesity published by Wiley Periodicals, Inc. on behalf of The Obesity Society (TOS).
PY - 2020/3/1
Y1 - 2020/3/1
N2 - Objective: Early life physical activity may help prevent obesity, but objective quantification in infants is challenging. Methods: A total of 506 infants were examined from 2013 to 2016. Infants wore accelerometers for 4 days at ages 3, 6, 9, and 12 months. Daily log-transformed physical activity counts were computed, averaged, and standardized across assessments. A linear mixed model was used to examine trends in standardized physical activity counts as well as associations between physical activity and BMI z score, sum of subscapular and triceps skinfold thickness for overall adiposity (SS+TR), and their ratio for central adiposity (SS:TR). Results: Among infants, 66% were black and 50% were female. For each additional visit, standardized physical activity counts increased by 0.23 (CI: 0.18 to 0.27; P < 0.0001). This translates to 126.3 unadjusted physical activity counts or a 4% increase for each visit beyond 3 months. In addition, a 1-SD increase in standardized physical activity counts (550 unadjusted physical activity counts) was associated with a 0.01-mm lower SS:TR (95% CI: −0.02 to −0.001; P = 0.03). However, standardized physical activity counts were not associated with BMI z score or SS+TR. Conclusions: Physical activity increased over infancy and was associated with central adiposity. Despite limitations, researchers should consider objective measurement in infants.
AB - Objective: Early life physical activity may help prevent obesity, but objective quantification in infants is challenging. Methods: A total of 506 infants were examined from 2013 to 2016. Infants wore accelerometers for 4 days at ages 3, 6, 9, and 12 months. Daily log-transformed physical activity counts were computed, averaged, and standardized across assessments. A linear mixed model was used to examine trends in standardized physical activity counts as well as associations between physical activity and BMI z score, sum of subscapular and triceps skinfold thickness for overall adiposity (SS+TR), and their ratio for central adiposity (SS:TR). Results: Among infants, 66% were black and 50% were female. For each additional visit, standardized physical activity counts increased by 0.23 (CI: 0.18 to 0.27; P < 0.0001). This translates to 126.3 unadjusted physical activity counts or a 4% increase for each visit beyond 3 months. In addition, a 1-SD increase in standardized physical activity counts (550 unadjusted physical activity counts) was associated with a 0.01-mm lower SS:TR (95% CI: −0.02 to −0.001; P = 0.03). However, standardized physical activity counts were not associated with BMI z score or SS+TR. Conclusions: Physical activity increased over infancy and was associated with central adiposity. Despite limitations, researchers should consider objective measurement in infants.
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U2 - 10.1002/oby.22738
DO - 10.1002/oby.22738
M3 - Article
C2 - 31944621
AN - SCOPUS:85078069816
SN - 1930-7381
VL - 28
SP - 631
EP - 637
JO - Obesity
JF - Obesity
IS - 3
ER -