Phototransduction Motifs and Variations

King Wai Yau; Roger C. Hardie

doi:10.1016/j.cell.2009.09.029

Phototransduction Motifs and Variations

King Wai Yau, Roger C. Hardie

School of Medicine

Research output: Contribution to journal › Review article › peer-review

258 Scopus citations

Abstract

Seeing begins in the photoreceptors, where light is absorbed and signaled to the nervous system. Throughout the animal kingdom, photoreceptors are diverse in design and purpose. Nonetheless, phototransduction-the mechanism by which absorbed photons are converted into an electrical response-is highly conserved and based almost exclusively on a single class of photoproteins, the opsins. In this Review, we survey the G protein-coupled signaling cascades downstream from opsins in photoreceptors across vertebrate and invertebrate species, noting their similarities as well as differences.

Original language	English (US)
Pages (from-to)	246-264
Number of pages	19
Journal	Cell
Volume	139
Issue number	2
DOIs	https://doi.org/10.1016/j.cell.2009.09.029
State	Published - Oct 16 2009

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2009.09.029

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Phototransduction Motifs and Variations

Abstract

ASJC Scopus subject areas

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