Phototransduction in mouse rods and cones

Yingbin Fu, King Wai Yau

Research output: Contribution to journalReview articlepeer-review

177 Scopus citations


Phototransduction is the process by which light triggers an electrical signal in a photoreceptor cell. Image-forming vision in vertebrates is mediated by two types of photoreceptors: the rods and the cones. In this review, we provide a summary of the success in which the mouse has served as a vertebrate model for studying rod phototransduction, with respect to both the activation and termination steps. Cones are still not as well-understood as rods partly because it is difficult to work with mouse cones due to their scarcity and fragility. The situation may change, however.

Original languageEnglish (US)
Pages (from-to)805-819
Number of pages15
JournalPflugers Archiv European Journal of Physiology
Issue number5
StatePublished - Aug 2007


  • Cones
  • Mouse
  • Phototransduction
  • Rods

ASJC Scopus subject areas

  • Physiology
  • Clinical Biochemistry
  • Physiology (medical)


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