Photosensitive complex partial seizures aggravated by phenytoin

Avinoam Shuper; Eileen P.G. Vining

doi:10.1016/0887-8994(91)90034-I

Photosensitive complex partial seizures aggravated by phenytoin

Avinoam Shuper, Eileen P.G. Vining

School of Medicine

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

A 10-year-old girl is described with pure photosensitive complex partial seizures which consisted of a frightening visual phenomenon of seeing "shadow people", then staring blankly with lip smacking and sometimes becoming limp. The seizures were triggered by bright sunlight. With the institution of phenytoin therapy, her seizure frequency increased dramatically without any clinical evidence of toxicity and her phenytoin blood levels were within the therapeutic range. Discontinuation of phenytoin led to a return to baseline seizure frequency. The mechanism by which antiepileptic drugs may aggravate seizures is still not understood; therefore, awareness of this phenomenon is crucial for early diagnosis and appropriate treatment.

Original language	English (US)
Pages (from-to)	471-472
Number of pages	2
Journal	Pediatric Neurology
Volume	7
Issue number	6
DOIs	https://doi.org/10.1016/0887-8994(91)90034-I
State	Published - 1991

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Neurology
Developmental Neuroscience
Clinical Neurology

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10.1016/0887-8994(91)90034-I

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Photosensitive complex partial seizures aggravated by phenytoin

Abstract

ASJC Scopus subject areas

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