TY - JOUR
T1 - Photopigment bleaching phenomenon with scanning laser ophthalmoscopy and fluorescein angiography
AU - Breazzano, Mark P.
AU - Fernandez-Avellaneda, Pedro
AU - Kurup, Shree K.
AU - Freund, K. Bailey
N1 - Funding Information:
Originally submitted November 6, 2018. Revision received November 6, 2018. Accepted for publication March 25, 2019. Supported by The Macula Foundation, Inc., New York, NY. Dr. Freund is a consultant to Allergan, Novartis, Optovue, Zeiss, and Heidelberg Engineering and receives research support from Genentech/Roche. The remaining authors report no relevant financial disclosures. Address correspondence to K. Bailey Freund, MD, Vitreous Retina Macula Consultants of New York, 950 Third Ave. New York, NY 10022; email: [email protected]. doi: 10.3928/23258160-20190905-09
Publisher Copyright:
© 2019 Slack Incorporated. All rights reserved.
PY - 2019
Y1 - 2019
N2 - Photopigment bleaching occurs with saturation of photoreceptor pigment by shortwavelength fundus autofluorescence imaging. This phenomenon is seen as characteristic hyperautofluorescence with subsequent imaging acquisition. Herein, a patient with multiple sclerosis was found to exhibit increased choroidal hyperfluorescence during fluorescein angiography (FA) that corresponded with a circumscribed area of intense blue light exposure during initial scanning laser ophthalmoscopy. To the authors' knowledge, this case is the first description of photobleaching phenomenon during FA and should be recognized as nonpathologic by the clinician.
AB - Photopigment bleaching occurs with saturation of photoreceptor pigment by shortwavelength fundus autofluorescence imaging. This phenomenon is seen as characteristic hyperautofluorescence with subsequent imaging acquisition. Herein, a patient with multiple sclerosis was found to exhibit increased choroidal hyperfluorescence during fluorescein angiography (FA) that corresponded with a circumscribed area of intense blue light exposure during initial scanning laser ophthalmoscopy. To the authors' knowledge, this case is the first description of photobleaching phenomenon during FA and should be recognized as nonpathologic by the clinician.
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U2 - 10.3928/23258160-20190905-09
DO - 10.3928/23258160-20190905-09
M3 - Article
C2 - 31589758
AN - SCOPUS:85072971803
SN - 2325-8160
VL - 50
SP - 590
EP - 592
JO - Ophthalmic Surgery Lasers and Imaging Retina
JF - Ophthalmic Surgery Lasers and Imaging Retina
IS - 9
ER -