Photon migration theory applied to 3D optical imaging of tissue

Amir H. Gandjbakhche, Israel Gannot, Robert F. Bonner

Research output: Contribution to journalConference articlepeer-review


The random walk theory was used to addressed the interrelated elements required for clinically useful imaging, by calculating a time-dependent contrast function to describe photon paths in time-resolved transillumination detection of abnormally absorbing and scattering regions in tissue. Results of the theory were applied to estimate the absorption and the scattering coefficients of a cylinder embedded in a tissue-like phantom. A random walk model was applied for the characterization of photon paths within the tissue as a basis for inverse imaging algorithms. The model for photon migration used found exact expression for the frequency-dependent fluorescent signal emitted from a single fluorescent site embedded in tissue.

Original languageEnglish (US)
Number of pages1
JournalConference Proceedings - Lasers and Electro-Optics Society Annual Meeting-LEOS
StatePublished - Dec 1 1996
Externally publishedYes
EventProceedings of the 1996 9th Annual Meeting of IEEE Lasers and Electro-Optics Society, LEOS'96. Part 1 (of 2) - Boston, MA, USA
Duration: Nov 18 1996Nov 19 1996

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering


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