Phorbol ester receptors: Autoradiographic identification in the developing rat

K. M.M. Murphy; R. J. Gould; M. L. Oster-Granite; J. D. Gearhart; Solomon H. Snyder

doi:10.1126/science.6316499

Phorbol ester receptors: Autoradiographic identification in the developing rat

K. M.M. Murphy, R. J. Gould, M. L. Oster-Granite, J. D. Gearhart, Solomon H. Snyder

School of Medicine

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49 Scopus citations

Abstract

Autoradiography with ³H-labeled phorbol dibutyrate was used for the light microscopic detection of phorbol ester receptors in rat fetuses. In 15- and 18-day fetuses, as well as in adult rats, receptors were found to be concentrated in the central nervous system. The localization ofreceptors in the ventral marginal zone of the fetal neural tube, the lens of the eye, and other sites suggests a role for phorbol ester receptors in cellular process extension and cell-cell interaction.

Original language	English (US)
Pages (from-to)	1036-1038
Number of pages	3
Journal	Science
Volume	222
Issue number	4627
DOIs	https://doi.org/10.1126/science.6316499
State	Published - 1983

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title = "Phorbol ester receptors: Autoradiographic identification in the developing rat",

abstract = "Autoradiography with 3H-labeled phorbol dibutyrate was used for the light microscopic detection of phorbol ester receptors in rat fetuses. In 15- and 18-day fetuses, as well as in adult rats, receptors were found to be concentrated in the central nervous system. The localization ofreceptors in the ventral marginal zone of the fetal neural tube, the lens of the eye, and other sites suggests a role for phorbol ester receptors in cellular process extension and cell-cell interaction.",

author = "Murphy, {K. M.M.} and Gould, {R. J.} and Oster-Granite, {M. L.} and Gearhart, {J. D.} and Snyder, {Solomon H.}",

year = "1983",

doi = "10.1126/science.6316499",

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volume = "222",

pages = "1036--1038",

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T2 - Autoradiographic identification in the developing rat

AU - Murphy, K. M.M.

AU - Gould, R. J.

AU - Oster-Granite, M. L.

AU - Gearhart, J. D.

AU - Snyder, Solomon H.

PY - 1983

Y1 - 1983

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AB - Autoradiography with 3H-labeled phorbol dibutyrate was used for the light microscopic detection of phorbol ester receptors in rat fetuses. In 15- and 18-day fetuses, as well as in adult rats, receptors were found to be concentrated in the central nervous system. The localization ofreceptors in the ventral marginal zone of the fetal neural tube, the lens of the eye, and other sites suggests a role for phorbol ester receptors in cellular process extension and cell-cell interaction.

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SP - 1036

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JF - Science

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ER -

Phorbol ester receptors: Autoradiographic identification in the developing rat

Abstract

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