Phase-sensitive Black-blood coronary vessel wall imaging

Khaled Z. Abd-Elmoniem, Robert G. Weiss, Matthias Stuber

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Black-blood MR coronary vessel wall imaging may become a powerful tool for the quantitative and noninvasive assessment of atherosclerosis and positive arterial remodeling. Although dual-inversion recovery is currently the gold standard, optimal lumen-to-vessel wall contrast is sometimes difficult to obtain, and the time window available for imaging is limited due to competing requirements between blood signal nulling time and period of minimal myocardial motion. Further, atherosclerosis is a spatially heterogeneous disease, and imaging at multiple anatomic levels of the coronary circulation is mandatory. However, this requirement of enhanced volumetric coverage comes at the expense of scanning time. Phase-sensitive inversion recovery has shown to be very valuable for enhancing tissue-tissue contrast and for making inversion recovery imaging less sensitive to tissue signal nulling time. This work enables multislice black-blood coronary vessel wall imaging in a single breath hold by extending phase-sensitive inversion recovery to phase-sensitive dual-inversion recovery, by combining it with spiral imaging and yet relaxing constraints related to blood signal nulling time and period of minimal myocardial motion.

Original languageEnglish (US)
Pages (from-to)1021-1030
Number of pages10
JournalMagnetic resonance in medicine
Issue number4
StatePublished - May 2010


  • Black-blood
  • Coronary artery
  • Dual inversion
  • Inversion recovery
  • Phasesensitive
  • Vessel wall

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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