Pharmacotherapy of Tourette's syndrome and associated disorders

D. J. Cohen, M. A. Riddle, J. F. Leckman

Research output: Contribution to journalReview articlepeer-review

41 Scopus citations


Tourette's syndrome (TS) is a chronic neuropsychiatric disorder characterized by multiform motor and phonic tics. Conditions that are commonly associated with TS include attention deficit hyperactivity disorder (ADHD) and obsessive compulsive disorder (OCD). Medications used to treat tics include haloperidol, pimozide, and clonidine. Symptoms of ADHD may respond to clonidine or desipramine. Specific serotonin uptake inhibitors, such as fluoxetine or clomipramine, are used in the treatment of OCD symptoms. The decision to use medication and the monitoring of its impact require careful assessment of the child's overall development and not only the presence of tic symptoms.

Original languageEnglish (US)
Pages (from-to)109-129
Number of pages21
JournalPsychiatric Clinics of North America
Issue number1
StatePublished - 1992
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health


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