Pharmacotherapy for treatment of complex regional pain syndrome

Emmett E. Whitaker; Michael Erdek

doi:10.1097/WNQ.0b013e31818d5813

Pharmacotherapy for treatment of complex regional pain syndrome

Emmett E. Whitaker, Michael Erdek

School of Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

Complex regional pain syndrome (CRPS) is an ill-defined, poorly understood disorder that causes significant morbidity in those who suffer from it. It is estimated that up to 20% to 35% of patients will remain incapacitated indefinitely and that only 20% to 30% of patients will be able to return to their previous full-time employment. A number of treatments, interventional and noninterventional, have been posited as possible therapies for CRPS. We discuss and review here the evidence-based rationale for pharmacologic therapy for CRPS.

Original language	English (US)
Pages (from-to)	277-282
Number of pages	6
Journal	Neurosurgery Quarterly
Volume	18
Issue number	4
DOIs	https://doi.org/10.1097/WNQ.0b013e31818d5813
State	Published - Dec 1 2008

Keywords

Anticonvulsant
CRPS
Calcium channel blocker
Clonidine
Complex regional pain syndrome
DMSO
Free radical scavengers
Gabapentin
Lidocaine patch
Memantine
NSAIDs
Nifedipine
Opioids
Pregabalin
Systemic lidocaine
TCA
Thalidomide
Tricyclic antidepressant

ASJC Scopus subject areas

Surgery
Clinical Neurology

Access to Document

10.1097/WNQ.0b013e31818d5813

Cite this

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abstract = "Complex regional pain syndrome (CRPS) is an ill-defined, poorly understood disorder that causes significant morbidity in those who suffer from it. It is estimated that up to 20% to 35% of patients will remain incapacitated indefinitely and that only 20% to 30% of patients will be able to return to their previous full-time employment. A number of treatments, interventional and noninterventional, have been posited as possible therapies for CRPS. We discuss and review here the evidence-based rationale for pharmacologic therapy for CRPS.",

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AU - Whitaker, Emmett E.

AU - Erdek, Michael

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N2 - Complex regional pain syndrome (CRPS) is an ill-defined, poorly understood disorder that causes significant morbidity in those who suffer from it. It is estimated that up to 20% to 35% of patients will remain incapacitated indefinitely and that only 20% to 30% of patients will be able to return to their previous full-time employment. A number of treatments, interventional and noninterventional, have been posited as possible therapies for CRPS. We discuss and review here the evidence-based rationale for pharmacologic therapy for CRPS.

AB - Complex regional pain syndrome (CRPS) is an ill-defined, poorly understood disorder that causes significant morbidity in those who suffer from it. It is estimated that up to 20% to 35% of patients will remain incapacitated indefinitely and that only 20% to 30% of patients will be able to return to their previous full-time employment. A number of treatments, interventional and noninterventional, have been posited as possible therapies for CRPS. We discuss and review here the evidence-based rationale for pharmacologic therapy for CRPS.

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KW - Calcium channel blocker

KW - Clonidine

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KW - DMSO

KW - Free radical scavengers

KW - Gabapentin

KW - Lidocaine patch

KW - Memantine

KW - NSAIDs

KW - Nifedipine

KW - Opioids

KW - Pregabalin

KW - Systemic lidocaine

KW - TCA

KW - Thalidomide

KW - Tricyclic antidepressant

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JO - Neurosurgery Quarterly

JF - Neurosurgery Quarterly

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Pharmacotherapy for treatment of complex regional pain syndrome

Abstract

Keywords

ASJC Scopus subject areas

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