Personalized therapy for acute myeloid leukemia

Christopher S. Hourigan, Judith E. Karp

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Patient-specific ex vivo drug sensitivity and resistance screening can identify rational drug candidates for the testing of personalized targeted therapy. An iterative approach of genomic and drug susceptibility characterization at sequential time points during clinical trials of targeted therapy in acute myeloid leukemia may be useful both for characterizing mechanisms of resistance and clonal evolution and also for identification of novel therapeutic targets and drug combinations.

Original languageEnglish (US)
Pages (from-to)1336-1338
Number of pages3
JournalCancer discovery
Issue number12
StatePublished - Dec 2013

ASJC Scopus subject areas

  • Oncology


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