Peripheral Arterial Disease

K. Matsushita, A. Barleben, M. Allison

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Herein, we define peripheral arterial disease (PAD) as a significant obstructive atherosclerosis in the arterial system of the lower extremities. Representative clinical manifestations of PAD include intermittent claudication and tissue loss of the feet or toes. Both are typically due to the extensive accumulation of atherosclerotic plaques that lead to tissue ischemia and, in the case of tissue loss, potentially necrosis. In some cases, arterial revascularization is performed to restore adequate oxygen supply distal to the obstruction.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Cardiovascular Research and Medicine
PublisherElsevier
Pages49-59
Number of pages11
Volume1-4
ISBN (Electronic)9780128051542
ISBN (Print)9780128096574
DOIs
StatePublished - Jan 1 2017
Externally publishedYes

Keywords

  • Ankle-brachial index
  • Critical limb ischemia
  • Peripheral arterial disease

ASJC Scopus subject areas

  • General Medicine

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