Performance of the CogState computerized battery in the Mayo Clinic Study on Aging

Michelle M. Mielke, Mary M. Machulda, Clinton E. Hagen, Kelly K. Edwards, Rosebud O. Roberts, V. Shane Pankratz, David S. Knopman, Clifford R. Jack, Ronald C. Petersen

Research output: Contribution to journalArticlepeer-review

43 Scopus citations


Introduction The feasibility and validity of brief computerized cognitive batteries at the population-level are unknown. Methods Nondemented participants (n = 1660, age 50-97 years) in the Mayo Clinic Study on Aging completed the computerized CogState battery and standard neuropsychological battery. The correlation between tests was examined and comparisons between CogState performance on the personal computer (PC) and iPad (n = 331), and in the clinic vs. at home (n = 194), were assessed. Results We obtained valid data on greater than 97% of participants on each test. Correlations between the CogState and neuropsychological tests ranged from -0.462 to 0.531. Although absolute differences between the PC and iPad were small and participants preferred the iPad, performance on the PC was faster. Participants performed faster on Detection, One Card Learning, and One Back at home compared with the clinic. Discussion The computerized CogState battery, especially the iPad, was feasible, acceptable, and valid in the population.

Original languageEnglish (US)
Pages (from-to)1367-1376
Number of pages10
JournalAlzheimer's and Dementia
Issue number11
StatePublished - Nov 1 2015
Externally publishedYes


  • Cognitively normal
  • Computerized cognitive battery
  • Epidemiology
  • Mild cognitive impairment
  • Neuropsychology
  • Population-based cohort study

ASJC Scopus subject areas

  • Clinical Neurology
  • Developmental Neuroscience
  • Cellular and Molecular Neuroscience
  • Psychiatry and Mental health
  • Geriatrics and Gerontology
  • Epidemiology
  • Health Policy


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