Percutaneous closure of patent ductus arteriosus: A multiinstitutional registry comparing multiple devices

Marissa A. Brunetti, Richard Ringel, Carl Owada, John Coulson, Jacky M. Jennings, Mark H. Hoyer, Allen D. Everett

Research output: Contribution to journalArticlepeer-review

55 Scopus citations


Background: There are no guidelines and multiple devices available now for closure of PDA. Objective: We sought to determine which devices are used and their outcomes. Methods: Prospectively collected data on closure of PDA at 12 US catheterization labs was entered into the MAGIC data registry between November 2005 and September 2008. Results: PDA closure was accomplished in 357 of 359 attempted closures during the study period. Mean age, weight, and minimum ductal diameter were 4.3 ± 6.8 years, 18.7 ± 18.4 kg, and 2.1 ± 1.4 mm, respectively. Devices used were Gianturco coils (161/359), Amplatzer Duct Occluder (ADO, 174/359), Flipper coils (18/359), and other devices (6/359). Gianturco coils had the least fluoroscopy and contrast exposure (8.7 ± 7.5 min, P = 0.00001, 2.6 ± 1.4 cm3 kg-1, P = 0.00001). Immediate angiographic success rates were 96.9% (156/161) for Gianturco coils, 89.7% (156/174) for the ADO, 100% (18/18) for Flipper coils, and 66.7% (4/6) for other devices. Major complication rates were 0.6% for Gianturco coils (1/161), 1.7% for ADO (3/174), and 83.3% for other devices (4/6). Minor complication rates by device were 1.9% for Gianturco coils (3/161), 2.3% for ADO (4/174), and 16.7% (1/6) for other devices. Conclusions: Gianturco coils, the ADO and Flipper coils were immediately successful with low complication profiles. The ADO and Gianturco coils were the predominate devices. The ADO was the device of choice for PDA > 3 mm with good success. In PDA < 3 mm, the Gianturco coil is as effective and safe as the ADO with less cost, less radiation, and less contrast exposure.

Original languageEnglish (US)
Pages (from-to)696-702
Number of pages7
JournalCatheterization and Cardiovascular Interventions
Issue number5
StatePublished - Nov 1 2010


  • cardiovascular abnormalities
  • congenital heart defects
  • heart catheterization

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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