Penile nerve block for newborn circumcision

L. G. Maxwell, M. Yaster, R. C. Wetzel, J. R. Niebyl

Research output: Contribution to journalArticlepeer-review

59 Scopus citations


Circumcision in neonates is performed, almost universally, without anesthesia or analgesia. It is associated with pain, crying, agitation, and physiologic stress. Twenty infants receiving penile nerve block for circumcision were compared with ten infants having circumcision without anesthesia. Heart rate and blood pressure rose 34 and 15%, respectively, in unblocked infants, and were unchanged in infants receiving local anesthesia. Oxygen saturation declined 16% in unanesthetized infants compared with 6% in blocked infants (P < .03). Anesthetized infants were less agitated and cried less. Peak plasma concentrations of the local anesthetic lidocaine averaged 0.51 ± 0.17 μg/mL (range 0.1-1.6), well below accepted toxic levels. There were no local or systemic complications.

Original languageEnglish (US)
Pages (from-to)415-419
Number of pages5
JournalObstetrics and gynecology
Issue number3 PART I
StatePublished - 1987
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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