Penile cancer with positive nodes: A case of HPV p16-positivity and its significance, implication of data from head and neck cancer

Cam Nguyen; Stephen Leslie; John Gross; Nicholas Dietz; Subodh M. Lele; Gopi Sirineni

doi:10.1016/j.eucr.2019.101009

Penile cancer with positive nodes: A case of HPV p16-positivity and its significance, implication of data from head and neck cancer

Cam Nguyen
, Stephen Leslie
, John Gross
, Nicholas Dietz
, Subodh M. Lele
, Gopi Sirineni

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Penile cancer is normally discovered in an early stage due to its visibility to the patient. This case report demonstrates a morbidly obese patient with a locally advanced penile cancer hidden by fatty tissue. Biopsy showed P16-positive tumor cells, which responded to concurrent chemo-radiotherapy with no evidence of disease at 24 months of follow-up. We also review the significance of p16-positive cell biology.

Original language	English (US)
Article number	101009
Journal	Urology Case Reports
Volume	27
DOIs	https://doi.org/10.1016/j.eucr.2019.101009
State	Published - Nov 2019
Externally published	Yes

Keywords

Anal cancer
Chemotherapy
HPV
Penile cancer
Radiotherapy
p16

ASJC Scopus subject areas

Urology

Access to Document

10.1016/j.eucr.2019.101009

Cite this

@article{aea9cfbd48e8442491fafa822b70a019,

title = "Penile cancer with positive nodes: A case of HPV p16-positivity and its significance, implication of data from head and neck cancer",

abstract = "Penile cancer is normally discovered in an early stage due to its visibility to the patient. This case report demonstrates a morbidly obese patient with a locally advanced penile cancer hidden by fatty tissue. Biopsy showed P16-positive tumor cells, which responded to concurrent chemo-radiotherapy with no evidence of disease at 24 months of follow-up. We also review the significance of p16-positive cell biology.",

keywords = "Anal cancer, Chemotherapy, HPV, Penile cancer, Radiotherapy, p16",

author = "Cam Nguyen and Stephen Leslie and John Gross and Nicholas Dietz and Lele, \{Subodh M.\} and Gopi Sirineni",

note = "Publisher Copyright: {\textcopyright} 2019",

year = "2019",

month = nov,

doi = "10.1016/j.eucr.2019.101009",

language = "English (US)",

volume = "27",

journal = "Urology Case Reports",

issn = "2214-4420",

publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Penile cancer with positive nodes

T2 - A case of HPV p16-positivity and its significance, implication of data from head and neck cancer

AU - Nguyen, Cam

AU - Leslie, Stephen

AU - Gross, John

AU - Dietz, Nicholas

AU - Lele, Subodh M.

AU - Sirineni, Gopi

PY - 2019/11

Y1 - 2019/11

N2 - Penile cancer is normally discovered in an early stage due to its visibility to the patient. This case report demonstrates a morbidly obese patient with a locally advanced penile cancer hidden by fatty tissue. Biopsy showed P16-positive tumor cells, which responded to concurrent chemo-radiotherapy with no evidence of disease at 24 months of follow-up. We also review the significance of p16-positive cell biology.

AB - Penile cancer is normally discovered in an early stage due to its visibility to the patient. This case report demonstrates a morbidly obese patient with a locally advanced penile cancer hidden by fatty tissue. Biopsy showed P16-positive tumor cells, which responded to concurrent chemo-radiotherapy with no evidence of disease at 24 months of follow-up. We also review the significance of p16-positive cell biology.

KW - Anal cancer

KW - Chemotherapy

KW - HPV

KW - Penile cancer

KW - Radiotherapy

KW - p16

UR - https://www.scopus.com/pages/publications/85071876476

UR - https://www.scopus.com/pages/publications/85071876476#tab=citedBy

U2 - 10.1016/j.eucr.2019.101009

DO - 10.1016/j.eucr.2019.101009

M3 - Article

AN - SCOPUS:85071876476

SN - 2214-4420

VL - 27

JO - Urology Case Reports

JF - Urology Case Reports

M1 - 101009

ER -

Penile cancer with positive nodes: A case of HPV p16-positivity and its significance, implication of data from head and neck cancer

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this