Pelvic pain and surgeries in women before interstitial cystitis/painful bladder syndrome

Patricia W. Langenberg, Edward E. Wallach, Daniel J. Clauw, Fred M. Howard, Christina M. Diggs, Ursula Wesselmann, Patty Greenberg, John W. Warren

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Objective: The objective of the study was to compare subjects with interstitial cystitis/painful bladder syndrome (IC/PBS) with controls on prior surgeries. Study Design: IC/PBS subjects were compared with matched controls on surgeries and possible surgical indications prior to their index dates. Results: Adjusted for demographic variables, logistic regression showed subjects exceeded controls in surgeries longer than 12 months and less than 1 month before the index date. However, addition of possible surgical indications showed chronic pelvic pain (CPP) to have a strong association with IC/PBS, whereas associations with surgeries were reduced to nonsignificance. Conclusion: Although women with IC/PBS were more likely to have experienced prior surgeries than controls, the apparent indications for surgeries, not the surgeries themselves, were stronger risk factors for IC/PBS. In particular, a prior history of CPP had a strong association with IC/PBS. Several features of study design, including extensive medical record review, suggest that prior CPP was not undiagnosed IC/PBS. Further investigation of CPP may yield insight into the pathogenesis of IC/PBS.

Original languageEnglish (US)
Pages (from-to)286.e1-286.e6
JournalAmerican journal of obstetrics and gynecology
Volume202
Issue number3
DOIs
StatePublished - Mar 2010

Keywords

  • chronic pelvic pain
  • fibromyalgia
  • hysterectomy
  • interstitial cystitis
  • oophorectomy
  • risk factor

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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