Pedigree study of familial alzheimer disease

Diane Powell, Marshal F. Folstein

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Twenty-one families with familial Alzheimer disease were ascertained in a dementia clinic and assessed by multiple family interviews. Eight autopsies were reviewed. The age of onset varied from 25 to 85. Seven pedigrees showed evidence of 3 generation transmission. Paternal age of the founders of 4 lines which could be assessed was higher than controls.

Original languageEnglish (US)
Pages (from-to)189-197
Number of pages9
JournalJournal of Neurogenetics
Issue number2
StatePublished - 1984


  • Alzheimer disease
  • Pedigree study

ASJC Scopus subject areas

  • Genetics
  • Cellular and Molecular Neuroscience


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