Pediatric Vision Screener 2: Pilot study in adults

Deborah S. Nassif, Nadya V. Piskun, Boris I. Gramatikov, David L. Guyton, David G. Hunter

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Amblyopia is a form of visual impairment caused by ocular, misalignment (strabismus) or defocus in an otherwise healthy eye. If detected early, the condition can be fully treated, yet over half of all children with amblyopia under age 5 escape detection. We developed a Pediatric Vision Screener (PVS) to detect amblyopia risk factors. This instrument produces a binocularity score to indicate alignment and a focus score to indicate focus. The purpose of this study is to assess the performance of the PVS by testing adults who were fully cooperative for testing. The study group includes 40 subjects (20 controls, 20 patients) aged 22 to 79 years. 12 patients had constant strabismus (8 to 50 Δ), and eight had variable strabismus (12 to 55 Δ). All controls had binocularity scores >50%. Binocularity was <50% in 11/12 patients. The patient with binocularity >50% had a well-controlled intermittent exotropia and was not at risk for amblyopia. Focus scores were highly sensitive for good focus but not specific. The PVS shows high sensitivity and specificity for detection of strabismus in adults. Future studies will determine whether this performance can be achieved in preschool children, who are at greatest risk for vision loss.

Original languageEnglish (US)
Pages (from-to)1369-1374
Number of pages6
JournalJournal of biomedical optics
Issue number6
StatePublished - Nov 2004


  • Amblyopia
  • Birefringence
  • Polarization optics
  • Strabismus
  • Vision screening

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering


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