Pediatric intestinal transplantation

Eliza J. Lee, George V. Mazariegos, Geoffrey J. Bond

Research output: Contribution to journalArticlepeer-review


Advancements in donor management, organ preservation and operative techniques, as well as immunosuppressive therapies, have provided children with intestinal failure and its complications a chance not only for enteral autonomy but also long-term survival through intestinal transplantation (ITx). First described in the 1960’s, experience has grown in managing these complex patients both pre- and post-transplant. The goals of this review are to provide a brief history of intestinal transplantation and intestinal rehabilitation in pediatric patients, followed by focused discussions of the indications for ITx, induction and maintenance immunosuppression therapies, common post-operative complications, and outcomes/quality of life post-transplant.

Original languageEnglish (US)
Article number151181
JournalSeminars in pediatric surgery
Issue number3
StatePublished - Jun 2022


  • Immunosuppression
  • Infection
  • Intestinal failure
  • Intestinal transplant
  • Post-transplant lymphoproliferative disease
  • Post-transplant outcomes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery


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