Pediatric dose selection

D. R. Abernethy, G. J. Burckart

Research output: Contribution to journalComment/debatepeer-review

25 Scopus citations


Selection of a drug dose in pediatrics is generally based on no or incomplete pharmacokinetic data. Traditionally, allometric, or scaling, techniques have been used; however, they have inherent limitations and may not make optimal use of the drug-specific clinical pharmacokinetic information that is available. Modeling is a tool that holds promise. The future challenge is to create a structured approach to determining pediatric doses for new therapeutic agents.

Original languageEnglish (US)
Pages (from-to)270-271
Number of pages2
JournalClinical pharmacology and therapeutics
Issue number3
StatePublished - Mar 2010
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)


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