Abstract
Case narrative Osteosarcoma is a highly malignant bone cancer with a predilection for spreading to the lungs that primarily affects adolescents. Non-metastatic osteosarcoma has an approximate cure rate of 70%. Patients with osteosarcoma and metastases at the time of diagnosis are cured less than 20% of the time. Treatment consists of surgery and chemotherapy. Many children with cancer are treated according to clinical research trials. Michael, a 15-year-old with metastatic osteosarcoma, has not responded to conventional therapy. For almost one year, he was treated on a therapeutic randomized clinical trial, which consisted of standard therapy (up-front chemotherapy, limb salvage surgery, and postsurgical chemotherapy). When his cancer responded poorly to up-front therapy he was randomized to receive additional “experimental” chemotherapy.
Original language | English (US) |
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Title of host publication | Clinical Ethics in Pediatrics |
Subtitle of host publication | A Case-Based Textbook |
Publisher | Cambridge University Press |
Pages | 1-6 |
Number of pages | 6 |
ISBN (Electronic) | 9780511740336 |
ISBN (Print) | 9780521173612 |
DOIs | |
State | Published - Jan 1 2011 |
Externally published | Yes |
ASJC Scopus subject areas
- General Medicine