Pediatric arterial ischemic stroke: Epidemiology, risk factors, and management

Ryan J. Felling, Lisa R. Sun, Emily C. Maxwell, Neil Goldenberg, Timothy Bernard

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Pediatric arterial ischemic stroke (AIS) is an uncommon but important cause of neurologic morbidity in neonates and children, with consequences including hemiparesis, intellectual disabilities, and epilepsy. The causes of pediatric AIS are unique to those typically associated with stroke in adults. Familiarity with the risk factors for AIS in children will help with efficient diagnosis, which is unfortunately frequently delayed. Here we review the epidemiology and risk factors for AIS in neonates and children. We also outline consensus-based practices in the evaluation and management of pediatric AIS. Finally we discuss the outcomes observed in this population. While much has been learned in recent decades, many uncertainties sill persist in regard to pediatric AIS. The ongoing development of specialized centers and investigators dedicated to pediatric stroke will continue to answer such questions and improve our ability to effectively care for these patients.

Original languageEnglish (US)
Pages (from-to)23-33
Number of pages11
JournalBlood Cells, Molecules, and Diseases
StatePublished - Sep 2017


  • Brain injury
  • Children
  • Infarct
  • Neonates

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology
  • Hematology
  • Cell Biology


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