TY - GEN
T1 - Patterned soft-micropolyhedra by self-folding and molding
AU - Pandey, Shivendra
AU - Yoon, Changkyu
AU - Zhang, Zhilin
AU - Kwag, Hye Rin
AU - Hong, Jinpyo
AU - Gracias, David H.
N1 - Publisher Copyright:
© 2016 IEEE.
PY - 2016/2/26
Y1 - 2016/2/26
N2 - It is extremely challenging to mass-produce polymeric microstructures with patterns in all three dimensions (3D). In this paper, we describe a highly parallel strategy to create such patterned soft-micropolyhedra with a range of polymers and even live mammalian cell-laden hydrogels. Specifically, we first patterned metallic micropolyhedra using photolithography and capillary force assisted self-folding. Inverse molds were created in the elastomer polydimethylsiloxane (PDMS); interestingly, the patterns were imprinted on the side walls of the molds. The molds were then filled with pre-polymers such as NOA73, PEGDA, and pNIPAM-AAc and cell-laden hydrogel solutions and cross-linked to form soft patterned micropolyhedra. Our results suggest that the combination of self-folding and molding could be used to create a variety of smart particles and building blocks with precisely patterned surfaces for applications in colloidal science, self-assembly, drug delivery and tissue engineering.
AB - It is extremely challenging to mass-produce polymeric microstructures with patterns in all three dimensions (3D). In this paper, we describe a highly parallel strategy to create such patterned soft-micropolyhedra with a range of polymers and even live mammalian cell-laden hydrogels. Specifically, we first patterned metallic micropolyhedra using photolithography and capillary force assisted self-folding. Inverse molds were created in the elastomer polydimethylsiloxane (PDMS); interestingly, the patterns were imprinted on the side walls of the molds. The molds were then filled with pre-polymers such as NOA73, PEGDA, and pNIPAM-AAc and cell-laden hydrogel solutions and cross-linked to form soft patterned micropolyhedra. Our results suggest that the combination of self-folding and molding could be used to create a variety of smart particles and building blocks with precisely patterned surfaces for applications in colloidal science, self-assembly, drug delivery and tissue engineering.
UR - https://www.scopus.com/pages/publications/84971014295
UR - https://www.scopus.com/pages/publications/84971014295#tab=citedBy
U2 - 10.1109/MEMSYS.2016.7421594
DO - 10.1109/MEMSYS.2016.7421594
M3 - Conference contribution
AN - SCOPUS:84971014295
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 203
EP - 206
BT - MEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016
Y2 - 24 January 2016 through 28 January 2016
ER -