Pattern of muscle involvement in inclusion body myositis: a sonographic study

Jemima Albayda, Lisa Christopher-Stine, Clifton O. Bingham, Julie J. Paik, Eleni Tiniakou, Seth Billings, O. Manny Uy, Philippe Burlina

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


OBJECTIVES: Imaging plays a role in myositis assessment by detecting muscle changes indicative of pathology. This study was conducted to determine the ultrasonographic pattern of muscle involvement in patients with inclusion body myositis (IBM) through an assessment of muscle echointensity. METHODS: Sixty-two individuals were consecutively studied, 18 with IBM, 16 with polymyositis or dermatomyositis and 28 normal controls. Standardised scans were completed bilaterally for the deltoids, biceps, flexor digitorum profundus (FDP), flexor carpi ulnaris, rectus femoris, tibialis anterior and gastrocnemius assessing for muscle echointensity changes. RESULTS: Patients with IBM had a markedly increased muscle echointensity when compared with comparator groups for all muscles studied. This was most discriminating at the FDP, gastrocnemius and rectus femoris. Asymmetry between sides and a heterogeneously increased echointensity were also seen. CONCLUSIONS: Ultrasonography can aid in the assessment of IBM by displaying an increased echointensity in characteristically involved muscles, particularly when combined with assessments for asymmetry and echotexture.

Original languageEnglish (US)
Pages (from-to)996-1002
Number of pages7
JournalClinical and experimental rheumatology
Issue number6
StatePublished - Nov 1 2018

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology


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