Pattern-evoked potentials and optic nerve fiber loss in monocular laser-induced glaucoma

M. A. Johnson; B. A. Drum; H. A. Quigley; R. M. Sanchez; G. R. Dunkelberger

Pattern-evoked potentials and optic nerve fiber loss in monocular laser-induced glaucoma

M. A. Johnson, B. A. Drum, H. A. Quigley, R. M. Sanchez, G. R. Dunkelberger

School of Medicine

Research output: Contribution to journal › Article › peer-review

91 Scopus citations

Abstract

ERG and VEP responses to counterphase checkerboard stimuli were obtained from cynomolgus monkeys with monocular glaucoma induced by laser photocoagulation of the trabecular meshwork. The glaucomatous eyes showed reductions of PERG amplitude that were directly related to the histologically defined nerve damage. VEP amplitudes were also reduced in the glaucomatous eyes, but were more variable and less affected by damage than the PERG responses. An acute increase in eye pressure to 40 mm Hg in eyes without damage had no detectable effect on PERG amplitudes.

Original language	English (US)
Pages (from-to)	897-907
Number of pages	11
Journal	Investigative Ophthalmology and Visual Science
Volume	30
Issue number	5
State	Published - 1989

ASJC Scopus subject areas

Ophthalmology
Sensory Systems
Cellular and Molecular Neuroscience

Cite this

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abstract = "ERG and VEP responses to counterphase checkerboard stimuli were obtained from cynomolgus monkeys with monocular glaucoma induced by laser photocoagulation of the trabecular meshwork. The glaucomatous eyes showed reductions of PERG amplitude that were directly related to the histologically defined nerve damage. VEP amplitudes were also reduced in the glaucomatous eyes, but were more variable and less affected by damage than the PERG responses. An acute increase in eye pressure to 40 mm Hg in eyes without damage had no detectable effect on PERG amplitudes.",

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AU - Drum, B. A.

AU - Quigley, H. A.

AU - Sanchez, R. M.

AU - Dunkelberger, G. R.

PY - 1989

Y1 - 1989

N2 - ERG and VEP responses to counterphase checkerboard stimuli were obtained from cynomolgus monkeys with monocular glaucoma induced by laser photocoagulation of the trabecular meshwork. The glaucomatous eyes showed reductions of PERG amplitude that were directly related to the histologically defined nerve damage. VEP amplitudes were also reduced in the glaucomatous eyes, but were more variable and less affected by damage than the PERG responses. An acute increase in eye pressure to 40 mm Hg in eyes without damage had no detectable effect on PERG amplitudes.

AB - ERG and VEP responses to counterphase checkerboard stimuli were obtained from cynomolgus monkeys with monocular glaucoma induced by laser photocoagulation of the trabecular meshwork. The glaucomatous eyes showed reductions of PERG amplitude that were directly related to the histologically defined nerve damage. VEP amplitudes were also reduced in the glaucomatous eyes, but were more variable and less affected by damage than the PERG responses. An acute increase in eye pressure to 40 mm Hg in eyes without damage had no detectable effect on PERG amplitudes.

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Pattern-evoked potentials and optic nerve fiber loss in monocular laser-induced glaucoma

Abstract

ASJC Scopus subject areas

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