Patient and provider perspectives on deprescribing proton pump inhibitors

Chisom Ikeji, Anne Williams, George Hennawi, Nicole J. Brandt

Research output: Contribution to journalArticlepeer-review


The aim of the current study is to describe proton pump inhibitor (PPI) prescribing trends in an older adult population and elucidate perspectives regarding PPI deprescribing. A retrospective chart review and a prospective cross-sectional analysis of provider and patient surveys were conducted. The retrospective chart review identified 107 patients age ≥65 who were prescribed PPI therapy. Nineteen patients on PPI therapy and 74 providers completed surveys regarding their perspectives on PPI deprescribing. PPI therapy was potentially inappropriate for 66% of patients based on dose, duration, and/or indication. Provider barriers to deprescribing included fear of outcomes, access to documentation, and uncertainty of current guidelines. This study illustrates the prevalence of long-term PPI use in geriatric patients without associated clinical indications, as well as perceived barriers to deprescribing. Long-term PPI use is associated with significant side effects; therefore, successful deprescribing must address these perceived barriers.

Original languageEnglish (US)
Pages (from-to)9-17
Number of pages9
JournalJournal of gerontological nursing
Issue number10
StatePublished - Sep 2019
Externally publishedYes

ASJC Scopus subject areas

  • Nursing(all)
  • Gerontology


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