Pathology of active infective endocarditis: a necropsy analysis of 192 patients.

E. N. Arnett, W. C. Roberts

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Successful treatment of infective endocarditis often requires cardiac valve replacement during the active infection. This is especially the case with aortic valve infection, and with infection of valve prostheses in either the aortic or mitral position. Valve excision with or without replacement, however, is also sometimes required for tricuspid valve infection (1). This discussion will focus on the morphologic aspects of active infective endocarditis involving both right and left-sided native cardiac valves. It will also examine certain morphologic aspects of mechanical and bioprosthetic valve substitutes. The information is derived from necropsy examination by the authors of 192 patients with active infective valvular endocarditis (Table 1). Of the 192 patients, 129 were described in an earlier publication (2). Patients with infective endocarditis complicating congenital heart disease with a shunt (6 patients), and those with infective endocarditis following valvulotomy (4 patients) are omitted from this analysis.

Original languageEnglish (US)
Pages (from-to)327-335
Number of pages9
JournalThe Thoracic and cardiovascular surgeon
Issue number6
StatePublished - Dec 1982

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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