Pathologic findings in adrenoleukodystrophy heterozygotes

J. M. Powers; H. W. Moser; A. B. Moser; C. K. Ma; S. B. Elias; R. A. Norum

Pathologic findings in adrenoleukodystrophy heterozygotes

J. M. Powers, H. W. Moser, A. B. Moser, C. K. Ma, S. B. Elias, R. A. Norum

Research output: Contribution to journal › Article › peer-review

Abstract

Two women, heterozygous for X-linked adrenoleukodystrophy, contained striated adrenocortical cells without inflammation and central nervous system demyelinative lesions. Only one was symptomatic neurologically; neither exhibited hypoadrenalism. These findings further document the variability of adrenoleukodystrophy heterozygotes and provide evidence that the major pathologic differences between hemizygote and heterozygote are quantitative in nature.

Original language	English (US)
Pages (from-to)	151-153
Number of pages	3
Journal	Archives of Pathology and Laboratory Medicine
Volume	111
Issue number	2
State	Published - Apr 13 1987
Externally published	Yes

ASJC Scopus subject areas

Pathology and Forensic Medicine
Medical Laboratory Technology

Cite this

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title = "Pathologic findings in adrenoleukodystrophy heterozygotes",

abstract = "Two women, heterozygous for X-linked adrenoleukodystrophy, contained striated adrenocortical cells without inflammation and central nervous system demyelinative lesions. Only one was symptomatic neurologically; neither exhibited hypoadrenalism. These findings further document the variability of adrenoleukodystrophy heterozygotes and provide evidence that the major pathologic differences between hemizygote and heterozygote are quantitative in nature.",

author = "Powers, {J. M.} and Moser, {H. W.} and Moser, {A. B.} and Ma, {C. K.} and Elias, {S. B.} and Norum, {R. A.}",

year = "1987",

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AU - Moser, H. W.

AU - Moser, A. B.

AU - Ma, C. K.

AU - Elias, S. B.

AU - Norum, R. A.

PY - 1987/4/13

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N2 - Two women, heterozygous for X-linked adrenoleukodystrophy, contained striated adrenocortical cells without inflammation and central nervous system demyelinative lesions. Only one was symptomatic neurologically; neither exhibited hypoadrenalism. These findings further document the variability of adrenoleukodystrophy heterozygotes and provide evidence that the major pathologic differences between hemizygote and heterozygote are quantitative in nature.

AB - Two women, heterozygous for X-linked adrenoleukodystrophy, contained striated adrenocortical cells without inflammation and central nervous system demyelinative lesions. Only one was symptomatic neurologically; neither exhibited hypoadrenalism. These findings further document the variability of adrenoleukodystrophy heterozygotes and provide evidence that the major pathologic differences between hemizygote and heterozygote are quantitative in nature.

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Pathologic findings in adrenoleukodystrophy heterozygotes

Abstract

ASJC Scopus subject areas

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