Pathogen Reduction: The State of the Science in 2019

Eric A. Gehrie; Sara J. Rutter; Edward L. Snyder

doi:10.1016/j.hoc.2019.05.001

Pathogen Reduction: The State of the Science in 2019

Eric A. Gehrie, Sara J. Rutter, Edward L. Snyder

School of Medicine

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

In the past 30 years, transfusion safety has increased substantially and blood transfusion is now a safer procedure than at any time in the past. Herein, we provide a comprehensive review of pathogen reduction, which is the new paradigm in transfusion safety. Specifically, we describe the various processes and technologies that are capable of diminishing or neutralizing infectious threats, including those that are not addressed or may not be detected by standard screening techniques. A special emphasis is placed on recent developments that are likely to impact patient care in 2019 and beyond.

Original language	English (US)
Pages (from-to)	749-766
Number of pages	18
Journal	Hematology/Oncology Clinics of North America
Volume	33
Issue number	5
DOIs	https://doi.org/10.1016/j.hoc.2019.05.001
State	Published - Oct 2019

Keywords

Blood transfusion
Pathogen reduction
Plasma transfusion
Platelet transfusion
Red blood cell transfusion
Transfusion-transmitted infection

ASJC Scopus subject areas

Hematology
Oncology

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10.1016/j.hoc.2019.05.001

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title = "Pathogen Reduction: The State of the Science in 2019",

abstract = "In the past 30 years, transfusion safety has increased substantially and blood transfusion is now a safer procedure than at any time in the past. Herein, we provide a comprehensive review of pathogen reduction, which is the new paradigm in transfusion safety. Specifically, we describe the various processes and technologies that are capable of diminishing or neutralizing infectious threats, including those that are not addressed or may not be detected by standard screening techniques. A special emphasis is placed on recent developments that are likely to impact patient care in 2019 and beyond.",

keywords = "Blood transfusion, Pathogen reduction, Plasma transfusion, Platelet transfusion, Red blood cell transfusion, Transfusion-transmitted infection",

author = "Gehrie, {Eric A.} and Rutter, {Sara J.} and Snyder, {Edward L.}",

year = "2019",

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AU - Rutter, Sara J.

AU - Snyder, Edward L.

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N2 - In the past 30 years, transfusion safety has increased substantially and blood transfusion is now a safer procedure than at any time in the past. Herein, we provide a comprehensive review of pathogen reduction, which is the new paradigm in transfusion safety. Specifically, we describe the various processes and technologies that are capable of diminishing or neutralizing infectious threats, including those that are not addressed or may not be detected by standard screening techniques. A special emphasis is placed on recent developments that are likely to impact patient care in 2019 and beyond.

AB - In the past 30 years, transfusion safety has increased substantially and blood transfusion is now a safer procedure than at any time in the past. Herein, we provide a comprehensive review of pathogen reduction, which is the new paradigm in transfusion safety. Specifically, we describe the various processes and technologies that are capable of diminishing or neutralizing infectious threats, including those that are not addressed or may not be detected by standard screening techniques. A special emphasis is placed on recent developments that are likely to impact patient care in 2019 and beyond.

KW - Blood transfusion

KW - Pathogen reduction

KW - Plasma transfusion

KW - Platelet transfusion

KW - Red blood cell transfusion

KW - Transfusion-transmitted infection

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Pathogen Reduction: The State of the Science in 2019

Abstract

Keywords

ASJC Scopus subject areas

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